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NITROBLUE TETRAZOLIUM |
| Synonyms. Nitroblue tetrazolium; NBT; Nitro Blue tetrazolium; Nitro Blue tetrazolium chloride; 5,5'-Diphenyl-3,3'-bis(4-nitrophenyl)-2,2'-(3,3'-dimethoxybiphenyl-4,4'-ylene)ditetrazolium dichloride; Nitro BT; Nitro tetrazolium BT; Nitroblue tetrazolium salt; Nitrotetrazolium Blue; Nitrotetrazolium Chloride Blue; p-Nitro Blue tetrazolium; p-Nitro Blue tetrazolium chloride; p-Nitrotetrazolium Blue; Tetrazolium Nitro Blue; Tetrazolium nitro BT; 2,2'-Bis(4-Nitrophenyl)-5,5'-diphenyl-3,3'-(3,3'-dimethoxy-4,4'-diphenylene)ditetrazolium chloride; 3,3'-(3,3'-Dimethoxy-4,4'-biphenylene)bis(2-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride); |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
298-83-9 |
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EINECS RN |
206-067-4 |
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FORMULA |
C40H30N10O6·2Cl |
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MOLE WEIGHT |
817.64 |
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H.S CODE |
2933.99.7900 |
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SMILES |
[n+]1(n(c2ccc([N+](=O)[O-])cc2)nc(n1)c1ccccc1)c1c(cc(c2cc(c([n+] 3n (c4ccc([N+](=O)[O-])cc4)nc(n3)c3ccccc3)cc2)OC)cc1)OC. [ClH-].[ClH-] |
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CLASSIFICATION |
Indicator, Substrate |
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EXTRA NOTES |
Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases, the latter causing neutrophils to reduce the dye; used to confirm diagnosis of chronic granulomatous disease.[MeSH] |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE |
light yellow crystalline powder |
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MELTING POINT |
189 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
10 mg/ml |
| SOLVENT SOLUBILITY |
Soluble in methanol |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 2, Flammability: 1, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Nitroblue tetrazolium Wikipedia Linking - Nitro blue tetrazolium chloride Google Scholar Search - Nitroblue tetrazolium U.S. National Library of Medicine - Nitroblue tetrazolium PubChem Compound Summary - Nitroblue tetrazolium KEGG (Kyoto Encyclopedia of Genes and Genomes) - Nitroblue tetrazolium ChEBI (http://www.ebi.ac.uk/chebi/) - Nitroblue tetrazolium NCBI (http://www.ncbi.nlm.nih.gov/) - Nitroblue tetrazolium Material Safety Data Sheet - Nitroblue tetrazolium Human Metabolome Database - Nitroblue tetrazolium EPA - Substance Registry Services - Nitroblue tetrazolium |
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| SALES SPECIFICATION | |
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APPEARANCE |
light yellow crystalline powder |
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ASSAY |
90% min |
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LOSS ON DRYING |
10.0% max |
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SULFATED ASH |
0.5% max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral, Dermal). Skin irritation. Eye irritation. Specific target organ toxicity - single exposure. Hazard statements: Harmful if swallowed. May be harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Causes damage to organs. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H302-H312-H313-H315-H317-H370-H371 |
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P STATEMENTS |
P260-P305 + P351 + P338-P307 + P311 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
20/21/22-39/23/24/25 |
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SAFETY PHRASES |
36/37 |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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| PRICE INFORMATION |
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